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Human Viral Diseases

Human Viral Diseases

1 quest

Completed: 40%

Challenge hub:

Illnesses due to viruses, from HIV to the common cold and new epidemics

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Sep 14, 2020

https://scitechdaily.com/computer-designed-synthetic-antiviral-proteins-inhibit-sars-cov-2-covid-19-in-human-cells/

Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19. In the experiments, the lead antiviral candidate, named LCB1, rivaled the best-known SARS-CoV-2 neutralizing antibodies in its protective actions.


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Sep 14, 2020

https://scitechdaily.com/ab8-covid-19-drug-breakthrough-tiny-antibody-component-completely-neutralizes-the-sars-cov-2-virus/

University of Pittsburgh School of Medicine scientists have isolated the smallest biological molecule to date that completely and specifically neutralizes the SARS-CoV-2 virus, which is the cause of COVID-19. This antibody component, which is 10 times smaller than a full-sized antibody, has been used to construct a drug — known as Ab8 — for potential use as a therapeutic and prophylactic against SARS-CoV-2.


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Sep 14, 2020

https://www.protocols.io/workspaces/xprct

Super cool workspace for the XPRIZE Rapid Covid Testing competition! Go check out many of these solutions from the open-science community.


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Sep 13, 2020

https://www.livescience.com/amp/brain-invasion-coronavirus.html

The coronavirus that causes COVID-19 can sometimes hijack brain cells, using the cells' internal machinery to copy itself, according to a new study.


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Sep 13, 2020

https://www.propublica.org/article/new-research-shows-disproportionate-rate-of-coronavirus-deaths-in-polluted-areas/amp

The type of pollution emitted by many chemical plants in Louisiana's industrial corridor is correlated with increased coronavirus deaths, according to new peer-reviewed research from SUNY and ProPublica.


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Sep 13, 2020

https://www.washingtonpost.com/world/2020/09/08/bergamo-italy-covid-longterm/?arc404=true

BERGAMO, Italy — The first wave is over, thousands have been buried, and in a city that was once the world’s coronavirus epicenter, the hospital is calling back the survivors. It is drawing their blood, examining their hearts, scanning their lungs, asking them about their lives.


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Sep 13, 2020

https://www.npr.org/sections/health-shots/2020/09/12/911987987/a-covid-19-vaccine-may-be-only-50-effective-is-that-good-enough?t=1599986815190

As we get closer to a COVID-19 vaccine, it's exciting to imagine a day when the virus is gone. But a vaccine will not be a magic bullet. In fact, it may be only about 50% effective.

SDG 3: Good health and well-being

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Sep 11, 2020

Humanitrack's overview of the latest and coming drug therapies for COVID-19 like Dexamethasone which has reduced mortality by 1/3rd for patients on ventilators, or other therapies like the exciting artificial antibodies like mNb6-tri (AeroNabs).


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Sep 07, 2020

https://www.ecronicon.com/ecpt/ECPT-08-00524.php

We used molecular docking as an approach to evaluate the binding energies of some already approved anti-parasitic drugs for their binding affinities to the main protease of COVID-19, otherwise known as the 3C-like protease or 3CL pro, (PDB ID: 6LU7). Molecular docking (blind) was done with the help of Autodock Vina. It was observed that of the seven drugs tested, two drugs, namely praziquantel (used for schistosomiasis) and amphotericin B (an antifungal drug) showed good binding energies with the protease and so merit further study for their potential use as therapeutic agents for COVID-19.

SDG 3: Good health and well-being

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Sep 03, 2020

https://www.sciencedaily.com/releases/2020/09/200902091108.htm

A blood test on hospital admission showing the presence or absence of SARS-CoV-2 can identify patients at a high risk of severe COVID-19, according to researchers. Admitted patients without virus in their blood have a good chance of rapid recovery.

SDG 3: Good health and well-being
covid-19
RNA
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Sep 03, 2020

https://factor.niehs.nih.gov/2020/9/feature/2-feature-glucocorticoid-drug/index.htm

Dexamethasone reduces dangerous inflammation seen late in the disease, say an NIEHS scientist and his collaborator. A synthetic glucocorticoid, dexamethasone is used for decades to treat conditions ranging from arthritis to immune system disorders.


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